Amycretin (zenagamtide)

Also known as: zenagamtide

Browse our Amycretin (zenagamtide) articles and comparisons. Start with the drug explainer for the mechanism and trial evidence, or choose a comparison below.

Profile at a glance

AttributeValue
SponsorNovo Nordisk
MechanismUnimolecular GLP-1 + amylin dual agonist
AdministrationOnce-daily oral tablet OR once-weekly subcutaneous injection
Peak weight loss~22% subq at 36 weeks / ~13.1% oral at 12 weeks (Phase 1)
StatusPhase 3 for obesity initiated Q1 2026

Drug explainer

What Is Amycretin (Zenagamtide)? Oral and Injectable Trial Data →

Novo Nordisk’s investigational GLP-1/amylin medicine has oral and injectable trials; the AMAZE Phase 3 program is underway.

See all drug profiles in the drug profiles hub or compare drugs head-to-head in the comparisons hub.